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Activated Oxygen: The Science Behind VetZone

Activated Oxygen: The Science Behind VetZone

Activated oxygen technology begins with medical-grade ozone (O₃), a highly reactive form of oxygen composed of three oxygen atoms. In controlled veterinary applications, ozone acts as a powerful oxidant with antimicrobial, anti-inflammatory, and immunomodulatory properties.

VetZoneRx formulations harness this activated oxygen by incorporating medical-grade ozone into stabilized ozonated oils, allowing the benefits of ozone to be delivered safely and effectively through topical application.


Why Activated Oxygen

Activated oxygen supports healing through three primary mechanisms:

• antimicrobial oxidation
• cellular energy activation
• inflammation modulation


Mechanism of Action

1. Antimicrobial Oxidation

Activated oxygen derived from ozone disrupts the membranes of bacteria, viruses, and fungi through oxidative stress. This process helps eliminate pathogens rapidly without relying on traditional antibiotics.

Scientific Source:
Bocci, V. (2006). Ozone: A New Medical Drug.


2. Cellular Energy Activation

Ozone-derived activated oxygen supports mitochondrial oxygen metabolism, helping enhance ATP production and supporting tissue repair and regeneration.

Scientific Source:
Elvis, A. M., & Ekta, J. S. (2011). Ozone therapy: A clinical review. J Nat Sci Biol Med.


3. Cytokine & Inflammation Modulation

Controlled ozone application helps regulate immune signaling and activate antioxidant defenses. This supports balanced inflammatory responses and may reduce swelling, redness, and tissue stress.


Why Ozonated Oils?

Stable & Safe

Ozonated oils store ozone safely as ozonides, allowing activated oxygen to be delivered topically without requiring refrigeration.

Deep Tissue Penetration

Our organic carrier oils enhance absorption through the skin and tissues.

Veterinarian Formulated

Developed by Dr. Meghan Qualls, DVM, with clinical insight from internal medicine specialist Dr. Heath Qualls, DVM.


Veterinary Clinical Applications

Condition Activated Oxygen Benefit
Wound infections (canine, equine) Disrupts bacterial biofilm and supports healing
Hoof rot, thrush, laminitis Supports oxygenation and healthy inflammatory response
Ear infections & otitis externa Antifungal and antibacterial support
Skin fold dermatitis Antimicrobial support without steroid reliance
Degloving injuries & abrasions Supports fibroblast activity and tissue repair

Veterinary Formulation Science

VetZoneRx ozonated formulations are crafted using:

• Medical-grade oxygen (USP 93% purity)
• Cold-pressed organic carrier oils
• Laboratory-verified ozone concentrations

Each formulation is designed to deliver activated oxygen safely, consistently, and effectively for animals.


Activated Oxygen. Harnessed.

Developed by veterinarians and trusted by animal owners, VetZoneRx formulations combine ozone-derived activated oxygen with carefully selected ingredients to support healing, skin health, and performance across species.