VetZone® Activating Wound Spray
A powerful, easy-to-apply wound care spray for pets, horses, and livestock. Harnessing ozone’s proven ability to combat bacteria, fungi, and viruses, this spray cleans and protects wounds while supporting faster healing. Also excellent for irritated skin, rain rot, scratches, and even red eyes.Key Benefits:
• Accelerates skin healing and tissue regeneration
• Eliminates bacteria, viruses, and fungi naturally
• Reduces oxidative stress and cellular damage
• Soothes itching, hives, and dermatitis
• Effective for burns, infections, wounds, and fungal issues
• Helps stimulate hair growth in affected areas
Gentle, fast-absorbing, and easy to apply—ideal for use on all animals needing skin support or wound care



VetZone® Activating Wound Spray
Client FAQs
It’s a gentle, yet highly effective topical spray made with medical-grade ozonated oils that deliver activated oxygen directly to the wound. This helps clean the area, control bacteria and fungi, and support your animal’s natural healing.
✅ Cuts, scrapes, and punctures
✅ Abrasions from fencing, tack, or training gear
✅ Red, irritated skin that might be at risk for infection
✅ Fungal or bacterial spots
Ozonated oils carry active oxygen to the wound, which gently helps disrupt harmful bacteria and fungi.
Improves blood flow around the area, so nutrients and oxygen can reach the tissue for faster recovery.
Supports clean, healthy new skin and hair growth.
The spray is great for covering larger areas, hard-to-reach spots, or wounds that are sensitive to touch.
The ointment is ideal for smaller wounds where you want more staying power and a bit of protective coverage.
Spray directly onto clean skin or wound once or twice daily.
No need to rinse off — let it air dry and continue with your usual care routine.
Most owners notice redness and swelling start to go down within 24-48 hours, with steady improvement as new skin grows over the next few days.
Yes! It’s formulated to be gentle on delicate tissue and is safe for horses, show pigs, goats, cattle, dogs, and more.
Veterinary Formulation Notes
The Use of Ozonated Wound Spray in Equine and Companion Animal Practice
Overview:
Ozonated wound sprays utilize stabilized ozonides created by infusing medical-grade ozone gas into carrier oils (often olive or sunflower). This process traps active oxygen species within the oil matrix, which are then slowly released upon application to biological tissues. As a result, ozonated sprays deliver sustained oxidative activity that is both antimicrobial and biostimulatory.
Mechanisms of Action
1. Antimicrobial Properties
Ozone (O₃) is a powerful oxidizing agent that disrupts microbial cell walls and membranes through lipid peroxidation, leading to cell lysis and death.
Effective against a wide spectrum of bacteria (Gram-positive & Gram-negative), fungi (including dermatophytes), and many enveloped viruses.
Helps reduce local bioburden in contaminated or infected wounds without fostering antimicrobial resistance.
2. Enhanced Tissue Oxygenation & Circulation
Ozonides stimulate local vasodilation, improving microcirculatory blood flow.
Increases oxygen tension in the wound bed, which is critical for fibroblast activity and collagen synthesis.
3. Modulation of Inflammation
Ozone normalizes prostaglandin E2 and reduces excessive reactive oxygen species by triggering upregulation of endogenous antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase).
Helps control prolonged inflammation that delays healing.
4. Stimulation of Cellular Repair
Promotes fibroblast proliferation and keratinocyte migration.
Accelerates granulation tissue formation and re-epithelialization.
Indications for Use
Acute wounds: Lacerations, abrasions, surgical incisions (post-primary closure as needed).
Chronic wounds:Non-healing ulcers, proud flesh (exuberant granulation tissue), pressure sores.
Contaminated wounds: Especially in environments with heavy bacterial load or when traditional antibiotics are to be minimized.
Dermatological infections: Adjunct in superficial fungal infections or interdigital dermatitis in livestock.
Practical Advantages
✅ Easy topical delivery: Spray format ensures uniform application over irregular surfaces, minimizes contact contamination, and reaches small crevices.
✅ No known risk of resistance: Unlike antibiotics, ozone’s oxidative mechanism does not promote resistant organisms.
✅ Can reduce reliance on systemic antibiotics: Especially useful in multi-resistant bacterial settings or where antibiotic stewardship is prioritized.
Veterinary Formulation Notes
Ozonated wound sprays are typically prepared at concentrations optimized for tissue tolerance (avoiding excessive oxidative irritation). Modern formulations use microencapsulation or specific ozonation protocols to ensure a stable, effective shelf life without rapid breakdown.
Summary
Ozonated wound sprays represent a versatile tool in veterinary wound management, combining broad-spectrum antimicrobial effects with enhanced oxygen delivery and modulation of local inflammatory processes. Their use supports faster, cleaner healing in both equine and small animal practice, making them particularly valuable in wounds at risk of chronicity or infection.
Why Vets Trust VetZone
Developed by Drs. Meghan Qualls, DVM, and Heath Qualls DVM, MS, DACVIM (LA), VetZone products are backed by clinical experience and crafted with precision. Every ingredient is chosen for efficacy, safety, and species sensitivity — because your animals deserve professional-grade care.
Need help choosing the right formula?
We are here to help! — (806) 790-9298