Ozone Therapy: Clinical Findings and Applications

Veterinary-Specific Studies

Ozone therapy in veterinary medicine: A review
Pérez-Torres, J. F. et al. (2019)
Link (PubMed)
→ Overview of veterinary applications in wound healing, musculoskeletal, and infectious diseases

Topical ozone therapy in the treatment of canine wounds
Vikartovska, A. et al. (2019)
Link (VetMed-Czech)
→ Case-controlled study showing ozone's effectiveness in healing canine skin wounds

Ozone therapy in the management of equine hoof infections
M. Díaz et al. (2015)
Link (NCBI)
→ Highlights use in thrush, laminitis, and abscesses

Mechanistic / Cellular Function

Ozone: A new medical drug
Bocci, V. (2005)
Link (Springer Book)
→ Landmark work detailing oxidative mechanisms and immune modulation in ozone therapy

Biological effects of ozone on human and animal cells
Elvis, A. M. & Ekta, J. S. (2011)
Link (Journal of Natural Science, Biology and Medicine)
→ Review covering ozone’s effect on mitochondria, cytokines, and cell membranes

The influence of ozone therapy on oxidative stress
Re, L. et al. (2008)
Link (Frontiers in Bioscience)
→ Describes antioxidant adaptation and systemic impact of medical ozone

Wound Healing and Inflammation

Ozone therapy for wound healing: A review of clinical applications
Karahasanoglu, A. et al. (2021)
Link (MDPI – Biomedicines)
→ Analyzes ozone’s efficacy for both acute and chronic wounds

Clinical use of ozone in diabetic foot ulcers
Lu, Y. et al. (2016)
Link (Wounds Journal)
→ While human-based, provides relatable mechanism and healing timelines

Clinical References

• Ozone therapy: A clinical review
• Topical ozonated oils in wound healing
• Ozone therapy in veterinary medicine